COMBINAISONS DE L'INHIBITEUR DE BTK GS-4059 AVEC DES INHIBITEURS CHOISIS PARMI UN INHIBITEUR DE JAK, D'ASK1, DE BRD ET/OU DE MMP9 POUR TRAITER LE CANCER, LES TROUBLES ALLERGIQUES,LES MALADIES AUTO-IMMUNES OU LES MALADIES INFLAMMATOIRES
DI PAOLO, JULIE,BRECKENRIDGE, DAVID,BATES, JAMIE,TUMAS, DANIEL
申请号:
CA3000746
公开号:
CA3000746A1
申请日:
2016.09.30
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided herein are methods that relate to a therapeutic strategy for treatment of cancer, and allergic, autoimmune, and inflammatory disorders including hematological malignancies. In particular, the methods include administration of a BTK inhibitor and with one or more inhibitor. For example, the one or more inhibitor may be a JAK inhibitor, a ASK1 inhibitor, a BRD4 inhitibor or an MMP9 inhibitor.