The University of British Columbia;UVic Industry Partnerships Inc.
发明人:
Mohsen Akbari,Brian Toyota
申请号:
US16169591
公开号:
US20200129435A1
申请日:
2018.10.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are embodiments of a composition comprising a matrix, a plurality of microparticles and a therapeutic agent. The therapeutic agent may be encapsulated in the microparticles, and/or the microparticles may be dispersed in the matrix. The composition may be a mesh or a sheet, and may further comprise a second therapeutic agent, and optionally a second microparticle and/or a second matrix. In particular embodiments, the matrix is a hydrogel. Methods for making and using the composition are also disclosed, and in certain embodiments, the composition is useful for treating cancer, such as brain cancer.