Method for selectively modifying a protein via transglutaminase catalyzed reaction

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专利权人:

Jens Buchardt

发明人:

Jens Buchardt,Nils Langeland Johansen

申请号：

US12674291

公开号：

US08586532B2

申请日:

2008.08.25

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates generally to a novel method of introducing property modifying groups to a protein. In particular, the present invention relates to the derivatization of lysine residues, as well as new conjugates of growth hormones with improved pharmacological properties, and methods for their preparation and use in therapy.

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