Embodiments of the present disclosure relate to a physiological sensing and therapeutic administration system. The system comprises a sensor and a pharmacokinetic (PK) server. The sensor (e.g., a physiological sensor) is configured to acquire real-time physiological measurements of a patient. The PK server is configured to determine a recommended administration of a therapeutic for the patient based on the acquired real-time physiological measurements of the patient. Due to the patient metabolizing therapeutic, the therapeutic has a time-varying concentration level in the patient. For instance, the concentration of the therapeutic in the patient decreases after an infusion.
