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AMIDE THIAZOLE DERIVATIVE, PREPARATION METHOD AND USES THEREOF
专利权人:
发明人:
申请号:
EP09832806.5
公开号:
EP2404909B1
申请日:
2009.11.30
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention relates to the field of the drugs associated with the diabetes. Particularly, the present invention relates to a dipeptidyl peptidase-IV inhibitor having the structure shown by formula (I), which contains amide thiazole structure and has an effect on treating diabetes, and a preparation method and a pharmaceutical composition containing it, as well as use thereof in manufacture of the drugs for treating the diabetes,wherein, R1 is hydrogen, halogen, C1-C5 alkyl, COOR3 or phenyl, wherein R3 is C1-C5 alkyl R2 is phenyl, substituted phenyl, 2-furanyl, substituted 2-furanyl, 2-thienyl, substituted 2-thienyl, 2-pyrrolyl, or substituted 2-pyrrolyl.
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