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METHOD FOR PURIFYING AND QUANTIFYING THROMBIN AND ITS DEGRADATION POLYPEPTIDES
专利权人:
Omrix Biopharmaceticals Ltd.
发明人:
Tamar AUERBACH-NEVO,Nadav ORR,Israel NUR
申请号:
US15922301
公开号:
US20180201917A1
申请日:
2018.03.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided is a method for purifying α-thrombin and for quantifying α-thrombin and its degradation polypeptides in a liquid proteinatious solution. The method employs a one-step anion exchange chromatography method. The method allows purification and/or quantification of a homogenous post-translationally modified α-thrombin. The method can also be used for purification and/or quantification of β-thrombin.
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