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Simulated moving bed chromatographic separation process
专利权人:
Angus Morrison;Rakesh Vikraman Nair Rema;Adam Kelliher;Anil Oroskar;Abhilesh Agarwal
发明人:
Adam Kelliher,Angus Morrison,Anil Oroskar,Rakesh Vikraman Nair Rema,Abhilesh Agarwal
申请号:
US13519618
公开号:
US09321715B2
申请日:
2010.12.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product, from a feed mixture, which process comprises introducing the feed mixture to a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous alcohol, wherein the apparatus has a plurality of zones comprising at least a first zone and second zone, each zone having an extract stream and a raffinate stream from which liquid can be collected from said plurality of linked chromatography columns, and wherein (a) a raffinate stream containing the PUFA product together with more polar components is collected from a column in the first zone and introduced to a nonadjacent column in the second zone, and/or (b) an extract stream containing the PUFA product together with less polar components is collected from a column in the second zone and introduced to a nonadjacent column in the first zone, said PUFA product being separated from different components of the feed mixture in each zone.
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