Henrik Oestergaard,Prafull S. Gandhi,Ole Hvilsted Olsen,Carsten Behrens,Paul L. DeAngelis,Friedrich Michael Haller
申请号：
US14936224
公开号：
US09370583B2
申请日:
2015.11.09
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.
