A magnetic drive medical handpiece includes a handpiece housing (1), and a magnetic power output assembly (20) and a magnetic power input assembly (30), where the magnetic power output assembly (20) is configured to be in connected transmission with a cutting tool, the magnetic power input assembly (30) is in transmission fit with a power apparatus and is configured to drive, by using magnetic force, the magnetic power output assembly (20) to rotate, and a separation member (2) configured to form an axial static seal is disposed between the magnetic power output assembly (20) and the magnetic power input assembly (30).