Northwestern University;THE RESEARCH FOUNDATION FOR THE STATE OF UNIVERSITY OF NEW YORK
发明人:
Jonathan Leis,Carol Carter
申请号:
US16361556
公开号:
US20190209589A1
申请日:
2019.03.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.