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17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE,USE THEREOF,AND MEDICAMENT CONTAINING SAID DERIVATIVE
专利权人:
BAYER SCHERING PHARMA AKTIENGESELLSCAFT
发明人:
KLAR ULRICH,KUHNKE JOACHIM,BOHLMANN ROLF,HUBNER JAN,RING SVEN,FRENZEL THOMAS,MENGES FREDERIK,BORDEN STEFFEN,MUHN HANS-PETER,PRELLE KATJA
申请号:
ZA201005397
公开号:
ZA201005397B
申请日:
2010.07.28
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
The invention relates to 17-(1′-propenyl)-17-3′-oxidoestra-4-en-3-one derivatives with the general chemical formula I, where the residues Z, R4, R6a, R6b, R7, R15, R16a, R16b and R18 have the meanings stated in Claim 1, and their solvates, hydrates and salts, including all stereoisomers of these compounds. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives, and in particular application in the aforementioned indications. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.
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中国工程科技知识中心
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