Fred Hutchinson Cancer Research Center;The Scripps Research Institute
发明人:
Gerald R. Smith,Susan K. Amundsen,Ahmet C. Karabulut,Thomas D. Bannister,Reji Narayanan Nair
申请号:
US15342056
公开号:
US20170305899A1
申请日:
2016.11.02
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed herein are compounds and methods for inhibiting bacterial DNA repair enzymes, including AddAB and RecBCD helicase-nucleases. Pharmaceutical compositions and methods for treating a subject with an antibacterial agent are also disclosed herein.