586302 Provided is a use of brimonidine or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for reducing post-surgical bleeding and/or bruising in a patient scheduled to be subjected to a surgical procedure, wherein the medicament is for topical application to the area of the skin of the patient where a surgical procedure that causes bleeding and/or bruising is scheduled to be performed, and wherein the medicament is to be administered either prior to performing the surgical procedure or after the procedure.