The invention belongs to the field of traditional Chinese medicine, and particularly relates to a new use of Pien Tze Huang and its preparation in the treatment of herpes zoster. Clinical studies have found that Pien Tze Huang combined with the antiviral drugs valacyclovir, acyclovir and mecobalamin have a definite curative effect on acute zoster herpes in liver stagnation, which not only promotes the improvement of clinical symptoms, but also promotes it quickly. Herpes scars, prevent the production of new herpes, relieve pain, and can shorten the treatment time, in addition to reduce the incidence of post-treatment neuralgia and the incidence of adverse reactions after treatment, clinical application has obvious advantages.本發明屬於中藥領域,具體涉及片仔癀及其製劑在治療帶狀皰疹中的新用途。臨床研究發現,片仔癀聯合抗病毒藥物伐昔洛韋、阿昔洛韋和甲鈷胺對肝經鬱熱型急性期帶狀皰疹有確切的療效,不僅能夠促進患者臨床症狀的改善,可快速促進皰疹的結痂、阻止新皰疹的產生、緩解疼痛,而且能夠縮短治療時間,此外還能降低治療後出現的後遺神經痛發病率和不良反應發生率,臨床應用具有明顯的優勢。