Belogurov, Aleksey Anatolievich,Ponomarenko, Natalia Alexandrovna,Gabibov, Alexandr Gabibovich
申请号:
AU2009354040
公开号:
AU2009354040A1
申请日:
2009.10.12
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Novel oligopeptides, combinations thereof and fusion proteins composed of the above-mentioned oligopeptides are disclosed. Oligopeptides are homologous in amino acid sequence to the selected parts of the amino acid sequence of human myelin basic protein (MBP) and are capable to ameliorate the progression of multiple sclerosis by means of binding to and inactivation of epitope-specific anti MBP auto antibodies (ESAMBPCAA) involved into binding and catalytic degradation of MBP in course of progression of Multiple Sclerosis.