The present invention relates to visualizing vascular structures. In order to provide further improved digital subtraction angiography, a device (10) for visualizing vascular structures is provided that comprises a data provision unit (12), a data processing module (14), and an output unit (16). The data provision unit is configured to provide a first sequence of non-contrast X-ray images of a region of interest of a patient for use as raw X-ray mask images. The data provision unit is also configured to provide a second sequence of contrast X-ray images of the region of interest of a patient for use as raw X-ray live-images. The processing unit is configured to perform a first spatial subtraction for the first sequence of non-contrast X-ray images resulting in a first sequence of spatial-subtracted mask images. The processing unit is also configured to perform a second spatial subtraction for the second sequence of contrast X-ray images resulting in a second sequence of spatial-subtracted X-ray live-images. The processing unit is further configured to perform a temporal subtraction by subtracting the spatial-subtracted mask images from the spatial-subtracted X-ray live-images resulting in a sequence of spatial-temporal subtracted X-ray live-images. The output unit is configured to output the sequence of spatial-temporal subtracted X-ray live-images.
