MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
发明人:
KREYSCH, HANS-GEORG,SCHMIDT, JUERGEN
申请号:
CA2501818
公开号:
CA2501818C
申请日:
2003.10.09
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to pharmaceutical compositions comprising differentmolecules, preferably monoclonal antibodies, each comprising epitopes thatbind simultaneously to different sites within the same ErbB 1 receptor domain.The preferred antibodies according to this invention are MAb 425 and MAb 225each in its murine, chimeric and humanized version. The invention relates tothe use and methods for an improved treatment of preferably tumors by means ofsaid compositions.