Institut Pasteur of Shanghai; Chinese Academy of Sciences
发明人:
Altmeyer Ralf,Peijun Ren
申请号：
US14384075
公开号：
US09872875B2
申请日:
2013.03.11
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method for treating viral infection includes administering to a subject in need thereof a composition containing P2X receptor antagonists. The methods may achieve preventive or therapeutic effect on hand foot and mouth disease by inhibiting viruses. The P2X receptor antagonists can inhibit infection by a positive-sense single-stranded RNA picornavirus. The virus may be an enterovirus or a Coxsackie virus, such as human enterovirus 71. The P2X receptor antagonist may be PPADS, iso-PPADS, PPNDS, Suramin, NF023, TNP-ATP, NF279, NF157, Evans Blue, an analog thereof, a derivative thereof, or a pharmaceutically acceptable salt thereof.
