Sebastien Febvay,Davide Maurizio Marini,David E. Clapham
申请号:
US13642210
公开号:
US20130289520A1
申请日:
2011.04.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides methods and compositions for highly precise spatial and temporal control over cytosolic delivery of compounds, in particular, those compounds that would otherwise be cell-impermeable. Among other things, the present invention provides a composition for targeted drug delivery comprising a nanoparticle, a targeting moiety specific for a cell type of interest, a light-activated drug delivery system, wherein the nanoparticles are associated with the targeting moiety and the light-activated drug delivery system.