您的位置: 首页 > 农业专利 > 详情页

RNAi AGENTS FOR HEPATITIS B VIRUS INFECTION
专利权人:
Arrowhead Pharmaceuticals; Inc.
发明人:
Zhen Li,Rui Zhu,Christine I. Wooddell,Bruce D. Given,Tao Pei,David L. Lewis,Lauren J. Almeida,David B. Rozema,Darren H. Wakefield
申请号:
US16267194
公开号:
US20190255091A1
申请日:
2019.02.04
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Described are compositions and methods for inhibition of Hepatitis B virus gene expression. RNA interference (RNAi) agents for inhibiting the expression of Hepatitis B virus gene are described. The HBV RNAi agents disclosed herein may be targeted to cells, such as hepatocytes, for example, by using conjugated targeting ligands. Pharmaceutical compositions comprising one or more HBV RNAi agents optionally with one or more additional therapeutics are also described. Delivery of the described HBV RNAi agents to infected liver in vivo provides for inhibition of HBV gene expression and treatment of diseases and conditions associated with HBV infection.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充