The present invention relates to the use of one or more compounds that arecapable of increasing the serum level of insulin-like growth factor 1 (IGF-1)for the preparation of a therapeutical composition, in particular in the formof a food supplement, for the treatment of subjects suffering from seriousfatigue and exhausting symptoms, burn-out and chronic fatigue syndrome. Thesame composition can also be used by patients suffering from depression,Alzheimer disease, irritated bowel syndrome, osteoporosis, type 2 diabetes, orfor anti-aging, immune therapy and recovery after exercise. The compositionalso has a use in veterinary applications for increasing the growth andimmunity in animals.
