Disclosed are lacrimal inserts and their method of use for delivery of of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye.本發明提供用於傳送藥物至眼部之淚管嵌入物及其使用方法。本發明之淚管塞包括一可通過淚點並置入眼瞼淚小管之主體。該淚管塞可包含一核心或貯藏器,於該本體部分中至少部分位包含一療劑,此療效劑係設置為可控制釋放至眼部。100...管狀淚管嵌入件101...滲透泵102...靜態阻力結構103...活塞104...末端閥元件105...微球體/膠囊106...活性劑配方110...腔室115...內壁面
