FIELD: medical equipment.SUBSTANCE: group of inventions relates to medical equipment, namely to medical portable injection devices like a pen-type injector, and, in particular, to the dose setting mechanisms for said devices. Dose setting mechanism for a drug delivery device comprises a dose setting member, drive member, clutch member, clicker. Clutch member is located between the dose setting member and the drive member. Clutch member is being axially movable relative to the dose setting member and to the drive member and being rotationally fixed to the drive member, providing a first clutch for rotationally coupling and de-coupling the dose setting member and the drive member. Clicker comprises a first clicker component and a second clicker component axially movable relative to each other for producing a tactile and/or audible feedback during relative rotational movement between them. First clicker component is axially movable relative to the drive member, providing a second clutch for rotationally coupling and de-coupling the drive member and the first clicker component. First clutch and the second clutch are designed and adapted to each other such that at any time during operation either the first clutch rotationally couples the dose setting member and the drive member, and/or the second clutch rotationally couples the drive member and the first clicker component. Injection device comprises said dose setting mechanism and a medicament, which is preferably contained in a cartridge.EFFECT: group of inventions provides an improved and compact dose setting mechanism with a clicker system that decreases the risk of malfunction.15 cl, 5 dwgГруппа изобретений относится к медицинской технике, а именно к медицинским портативным устройствам для инъекций перьевого типа, и, в частности, к механизмам установки дозы для указанных устройств. Механизм установки дозы для устройства доставки лекарственных средств содержит элемент установки дозы, элемент привода, элемент сцепления