Provided is a surgical instrument, including: a shaft a wrist member including a guide member, a wrist body connected to the guide member and formed with a plurality of installation holes, and a plurality of protruding members each disposed to face the wrist body and having an insertion groove, and connected to the shaft a plurality of effectors each connected to the wrist member by a pin a support driving unit having first through fourth rotation members inserted into pins that are mounted on the wrist member, respectively, and each first and second wires connected to the plurality of effectors and the first through fourth rotation members, respectively a main driving unit connected to the support driving unit by wire and having at least one driving unit. The main driving unit enables the entire wrist member to perform a yaw motion by rotating the entire wrist member, and enables the plurality of effectors to perform a pitch motion by simultaneously rotating the plurality of effectors into a single direction, and enables the plurality of effectors to perform a forceps motion of rotating into a direction increasing or decreasing a distance between the plurality of effectors.