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PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR MILD COGNITIVE IMPAIRMENT
专利权人:
FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION
发明人:
Masafumi Ihara,Takakuni Maki,Akihiko Taguchi
申请号:
US14407692
公开号:
US20150152084A1
申请日:
2013.06.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided is a prophylactic and/or therapeutic drug for mild cognitive impairment, which can improve interstitial flow in cerebral blood vessel and the like to achieve sufficient clearance of harmful proteins accumulated in the brain. The prophylactic and/or therapeutic drug includes 6-[4-(1-cyclohexyl-1H-tetrazole-5-yl)butoxy]3,4-dihydrocarbostyril or a salt thereof as an active ingredient. The prophylactic and/or therapeutic drug can improve a flow of interstitial fluid around blood vessels in a drainage pathway to excrete harmful proteins. The prophylactic and/or therapeutic drug for mild cognitive impairment may take the form of a pharmaceutical product for oral administration, a liquid pharmaceutical product for oral administration, or an injectable preparation. The prophylactic and/or therapeutic drug for mild cognitive impairment can be used for the prevention and/or treatment of cerebral amyloid angiopathy, and can also be used for improvement of Lewy body disease, Down's syndrome, or macular degeneration.
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