2,3-Fluoroglycosides as neuraminidase inhibitors and their use as antiviral agents

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专利权人:

ザ ユニヴァーシティ オヴ ブリティッシュ コロンビア

发明人:

ウィザーズ、ステファン,ワッツ、アンドリュー グラハム,キム、ジン ヒョ,ウェネケス、トム

申请号：

JP2012519854

公开号：

JP5855566B2

申请日:

2010.07.15

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The therapeutic effect is achieved via inhibition of viral neuraminidases, also known as viral sialidases. These neuraminidases are classified under the GH34 family of viral enzymes.

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