This creation system is that a kind of inhibition pet stomach Helicobacter pylori dental cleaning bone includes an aggregate ontology and a probiotics outer covering layer, and probiotics is cladded at least part outer surface that series of strata are cladded with what aggregate ontology, and a part system of probiotics outer covering layer penetrates into and inlays what aggregate ontology, the inhibition pet stomach Helicobacter pylori dental cleaning bone of this creation through pet what its oral occlusion, chew Hou and can effectively reduce the activity of stomach helicobacter pylori infection in pet's oral cavity. 本創作係為一種抑制寵物胃幽門螺旋桿菌潔牙骨包括一骨材本體及一益生菌外覆層,而益生菌外覆層係外覆於骨材本體之至少一部分外表面,且益生菌外覆層之一部分係滲入而鑲嵌於骨材本體,本創作之抑制寵物胃幽門螺旋桿菌潔牙骨經寵物於其口腔咬合、咀嚼後可有效降低寵物口腔中胃幽門桿菌的活性。