INC.;H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE
发明人:
Jacob Scott,Javier F. Torres-Roca
申请号：
US15571617
公开号：
US20180148791A1
申请日:
2016.05.05
申请国别(地区):
US
年份:
2018
代理人:
摘要：
An example method of treating a subject having a tumor is described herein. The method can include determining a radiosensitivity index of the tumor, deriving a subject-specific variable based on the radiosensitivity index, and obtaining a genomic adjusted radiation dose effect value for the tumor. The radiosensitivity index can be assigned from expression levels of signature genes of a cell of the tumor. Additionally, the genomic adjusted radiation dose effect value can be predictive of tumor recurrence in the subject after treatment. The method can also include determining a radiation dose based on the subject-specific variable and the genomic adjusted radiation dose effect value.
