The present disclosure relates to a bifunctional angiogenesis inhibitor, which has VEGF inhibitory activity and FGF inhibitory activity, and can inhibit VEGF and FGF dual factors-induced or high glucose-induced cell proliferation, cell migration, and/or lumen formation. The present disclosure also relates to the use of the bifunctional angiogenesis inhibitor in inhibiting retinal angiogenesis, such as diabetic retinopathy, age-related macular degeneration and the like.本發明涉及一種雙功能血管抑制劑，其具有VEGF抑制活性和FGF抑制活性，能夠抑制VEGF和FGF雙因數或者高糖誘導的細胞增殖、細胞遷移和/或管腔成形。本發明還涉及該雙功能血管抑制劑抑制視網膜血管生成的用途，如糖尿病視網膜病變，年齡相關黃斑變性等。
