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DERIVES DE BENZIMIDAZOLE-4-CARBOXAMIDE, LEURS PROCEDES D'ELABORATION, COMPOSITIONS PHARMACEUTIQUES ET LEURS UTILISATIONS
专利权人:
SHANGHAI JIAO TONG UNIVERSITY
发明人:
LUO, XIANJIN,XUE, FEI,ZHANG, ZHONGLV,XIU, NAIYUN
申请号:
CA2749174
公开号:
CA2749174C
申请日:
2010.01.06
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to the benzimidazole-4-carboxamide derivatives,theirpreparation methods, pharmaceutical compositions and their uses; wherein Xrepresentsmonosubstituted or bissubstituted or polysubstitued C1-C14 alkoxy,monosubstituted orbisubstituted or polysubstitued C1-C14 alkyl, monosubstituted or bisubstitutedorpolysubstitued C2-C14 alkenyl, monosubstituted or bisubstituted orpolysubstitued C6-C14aryl, or monosubstituted or bisubstituted or polysubstitued 5 to 6 memberedheterocyclicgroup, or monosubstituted or bisubstituted or polysubstitued fused ring groupcontainingnitrogen heteroatom; Y represents hydrogen, monosubstituted or bisubstitutedorpolysubstitued C1-C16 alkyl, monosubstituted or bisubstituted orpolysubstitued C6-C12 aryl,or monosubstituted or bisubstituted or polysubstitued 5 to 6 memberedheterocyclic group,or monosubstituted or bisubstituted or polysubstitued fused ring groupcontaining nitrogenheteroatom. The derivatives of the present invention have the functions ofantiviralmedicine.(see formula I)
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