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Condensed imidazole derivatives useful as IDO inhibitors
- 专利权人:
- Newlink Genetics Corporation
- 发明人:
- MAUTINO, Mario,KUMAR, Sanjeev,WALDO, Jesse,JAIPURI, Firoz,KESHARWANI, Tanay,ZHANG, Xiaoxia
- 申请号：
- ES15197593
- 公开号：
- ES2660831T3
- 申请日:
- 2012.04.12
- 申请国别(地区):
- ES
- 年份:
- 2018
- 代理人:
- 摘要：
- A pharmaceutical composition comprising a compound that is 2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanol； ethyl 2- (5H-imidazo [5,1-a] isoindol-5-yl) acetate； (E) -5- (2-Bromoestyryl) -5H-imidazo [5,1-a] isoindole； 2- (6-Chloro-5H-imidazo [5,1-a] isoindol-5-yl) -1-cyclohexyletanol； 2- (6-Chloro-5H-imidazo [5,1-a] isoindol-5-yl) -1-cyclohexyletanone； 2- (5H-imidazo [5,1-a] isoindol-5-yl) ethyl 2 - (((1R, 2R, 5S) -2-isopropyl-5-methylcyclohexyl) oxy) acetate； tert-butyl (4- (2- (SH-imidazo [5,1-a] isoindol-5-yl) acetyl) phenyl) carbamate； 1- (4-aminophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanone； tert-butyl (4- (1-hydroxy-2- (5H-imidazo [5,1-a] isoindol-5-yl) ethyl) phenyl) carbamate； 1- (4-aminophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanol； 1-cyclohexyl-2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanol； 2- (5H-imidazo [5,1-a] isoindol-5-yl) -I- (3-nitrophenyl) ethanone； 2- (5H-imidazo [5,1-a] isoindol-5-yl) -1- (3-nitrophenyl) ethanol； 2- (5H-imidazo [5,1-a] isoindol-5-yl) -1- (2-nitrophenyl) ethanone； 2- (5H-imidazo [5,1-a] isoindol-5-yl) -1- (2-nitrophenyl) ethanol； tert-butyl (2- (2- (5H-imidazo [5,1-a] isoindol-5-yl) acetyl) phenyl) carbamate； tert-butyl (2- (1-hydroxy-2- (5H-imidazo [5,1-a] isoindol-5-yl) ethyl) phenyl) carbamate； 1- (2-aminophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanone； 1- (2-aminophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanol； 1- (2-chlorophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanone； 1- (5H-imidazo [5,1-a] isoindol-5-yl) -2-methylpropan-2-ol； 1- (2-chlorophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanol； 1- (3-chlorophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanol； 2- (5H-imidazo [5,1-a] isoindol-5-yl) -1-phenyletanone； 2- (5H-imidazo [5,1-a] isoindol-5-yl) -1-phenylethanol； 1- (2,4-dimethylfuran-3-yl) -2- (6-fluoro-5H-imidazo [5,1-a] isoindol-5-yl) ethanol； 1- (3-chlorophenyl) -2- (5H-imidazo [5,1-a] isoindol-5-yl) ethanone； 1-cyclohexyl-2- (6-fluoro-5H-imidazo [5,1-a] isoindol-5-yl) ethan
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
