PROBLEM TO BE SOLVED: To provide a new angiogenesis, forming or stabilizing agent for a lymphatic vessel, as well as to provide a medicine which maintains and accelerates a recovering function of a lymphatic vessel and further improves or prevents dropsy or lymphedema by achieving angiogenesis, formation or stabilization of lymphatic vessel.SOLUTION: The problem is solved based on a finding that estrogen which targets an estrogen receptor contributes to angiogenesis, formation, or stabilization of lymphatic vessel.COPYRIGHT: (C)2013,JPO&INPIT【課題】新規のリンパ管新生、形成又は安定化剤の提供、並びにリンパ管新生、形成又は安定化を図ることにより、リンパ管の回収機能を維持・亢進し、ひいてはむくみ又はリンパ浮腫の改善又は予防する薬剤の提供。【解決手段】エストロゲン受容体を標的とするエストロゲンが、リンパ管新生、形成又は安定化に寄与することを見出すことに基づく。【選択図】図2
