Certain examples provide systems, methods, and apparatus for patient-enabled early health and prevention. An example patient preventive health system includes a monitoring application interface to receive data from one or more sensors positioned with respect to a patient. The system includes a sensor data processor to process the received data from the one or more sensors to identify one or more readings based on the received data. The system includes an event analyzer to process the one or more readings to generate an event output. The system includes a patient notifier to notify the patient based on the event output. The system includes a biomarker transmitter to identify and transmit a biomarker to a clinical research cloud based on the one or more readings.