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תרכובות ותכשירי רוקחות שלהן לטיפולים באי–סדרים דלקתיים
专利权人:
GALAPAGOS NV
发明人:
申请号:
IL25662417
公开号:
IL256624A
申请日:
2017.12.27
申请国别(地区):
IL
年份:
2019
代理人:
摘要:
The present invention discloses compounds according to Formula I: Wherein R 1a , R 1b , R 2 , R 4 , R 5 , R 6a , R 6b , R 7 , R 8 , W, X, Cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (NPP2 or ENPP2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, neurodegenerative diseases, dermatological disorders, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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