The present oral care compositions can soothe irritated oral mucous membranes, stimulates salivary secretion, and/or freshen breath. The oral care compositions can also be used to prevent and treat mucositis, gingivitis, periodontitis, mouth dryness (xerostomia), oral infections, oral inflammation, and halitosis. The compositions are especially useful in treating oral complications in cancer patients who have undergone chemotherapy or radiation therapy. The present composition contains natural ingredients and may be alcohol-free and/or free of artificial colors.