A method of delivering at least one therapeutic gas to a tissue site for treating acne, sunburn, scarring, a thermal burn, wrinkling, age spots, eczema, contact dermatitis, itching and a rash. The method comprises dissolving the gas in a liquid solvent that includes a thickening agent to create a solution, transporting that solution to the tissue site, and then releasing said gas at said tissue site for treating the skin-related ailment.