速效胰島素組合物农业专利-农业学术服务平台

发明人:: AKERS, MICHAEL PATRICK,亚克思　麦克　派翠克,亞克思　麥克　派翠克,PAAVOLA, CHAD D.,帕佛拉　查德Ｄ,SARIN, VIRENDER KUMAR,沙林　费伦德　库马,沙林　費倫德　庫馬,MAJUMDAR, RANAJOY,马将德　拉那乔伊,馬將德　拉那喬伊,NGUYEN, CHI A.,恩古彦　齐Ａ,恩古彥　齊Ａ,SCHULTE, NANETT,亚克思麦克派翠克,亞克思麥克派翠克,帕佛拉查德D,沙林费伦德库马,沙林費倫德庫馬,马将德拉那乔伊,馬將德拉那喬伊,恩古彦齐A,恩古彥齊A

摘要：: The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the addition of sodium chloride, zinc and, optionally, magnesium chloride and/or surfactant, and that has faster pharmacokinetic and/or pharmacodynamic action than commercial formulations of existing insulin analog products.本發明為一種人類胰島素或胰島素類似物之組合物，其包括特定濃度之檸檬酸鹽、氯化物，在一些情況下包括添加氯化鈉、鋅及視情況選用之氯化鎂及/或界面活性劑，且其具有比現有胰島素類似物產品之市售調配物快的藥物動力學及/或藥效學作用。