COMPOSES A FONCTIONNALITE MAGNETIQUE, IMPLANTS OU GELS DERIVES DE CES COMPOSES, ET UTILISATION DE CEUX-CI POUR DETERMINER L'ACTIVITE ENZYMATIQUE D'UNE ENZYME
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
发明人:
VELEZ TIRADO, MARISELA,DAICH, JULIAN
申请号:
CA2877058
公开号:
CA2877058A1
申请日:
2013.06.21
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to an implant or gel including at least one compound having magnetic functionality, which in turn includes a substrate of at least one enzyme involved in regenerating the extracellular matrix and a plurality of magnetic particles. The invention also relates to a compound having magnetic functionality which includes a substrate of at least one enzyme involved in regenerating the extracellular matrix and a plurality of magnetic particles, preferably with no coating or surface modification, or functionalised with carboxyl groups, for the production of an implant or gel for monitoring an enzyme activity involved in regenerating the extracellular matrix. The substrate is preferably selected from the group that comprises collagen, chondroitin sulphate and hyaluronic acid, and the magnetic particles are superparamagnetic particles.