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Monolithic Alginate IMPLANTS IN SITU
专利权人:
СЕЛЛМЕД АГ (DE)
发明人:
ВАЛЛЬРАПП Кристине (DE),ГЛЁКНЕР Херма (DE),РАЙНЕР Роланд (DE),ТЮРМЕР Франк (DE)
申请号:
RU2010133905/15
公开号:
RU2010133905A
申请日:
2009.01.09
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. The use of alginate in the preparation of an uncrosslinked, high-purity and high molecular weight alginate solution (sol) as a filler material in medicine or in cosmetology in order to increase the volume where the alginate is in an uncrosslinked, high-purity and high molecular weight alginate solution (sol) at a concentration of 0, 5 to 2.5% (w / v) of the alginate dry matter content, and the non-crosslinked, high-purity, and high molecular weight alginate solution administered in vivo leads in situ to spontaneous Ca2 + crosslinking without exogenous addition of crosslinking a cient. ! 2. The use according to claim 1, characterized in that the alginate is selected from high purity and high molecular weight alginates having an average molar mass of more than 200,000 Da, preferably from high purity and high molecular weight alginates having an average molar mass of from 200,000 to 5,000,000 Yes, more preferably from high purity and high molecular weight alginates having an average molar mass of 200,000 to 1,000,000 Da, and most preferably of high purity and high molecular weight alginates having an average molar mass of 200,000 to 500,000 Da. ! 3. The use according to claim 1, characterized in that the high-purity and high molecular weight potassium or sodium alginate is used as alginate. ! 4. The use according to any one of claims 1 to 3, characterized in that after the injection, the masses of the monolithic alginate implant are formed in situ at the injection site. ! 5. The use according to any one of claims 1 to 3, characterized in that the uncrosslinked, high-purity and high molecular weight alginate solution (sol) is present in a concentration of from 0.6 to 1.0% (w / v) of the dry matter content of alginate in in terms of the total mass. ! 6. Application according to any one of claims 1 to 3, excellent1. Применение альгината в получении несшитого, высокочистого и высокомолекулярного альгинатного раствора (золя) в качестве материала-наполнителя в медицине ил
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中国工程科技知识中心
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