NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT NIH DIVISION OF EXTRAMURAL INVENTIONS AND TECHNOLOGY RESOURCES (DEITR);ADVAXIS, INC.; INC.;ADVAXIS
发明人:
PETIT, ROBERT,WALLECHA, ANU,CHEN, ZHISONG,BERZOFSKY, JAY A.,KHLEIF, SAMIR
申请号：
SG11201607213Q
公开号：
SG11201607213QA
申请日:
2015.03.05
申请国别(地区):
SG
年份:
2016
代理人:
摘要：
The present invention is directed to methods for increasing T-cell effector cell to regulatory T cell ratio. The invention is further directed to methods of treating, protecting against, and inducing an immune response against a tumor, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO fragment and tumor-associated antigen.
