It can introduce into internal of the patient to medical application the hydrogel of freezing drying and the production method of the structure due to this are offered. The precusor component is combined in order to start building a bridge. It places in the plate which cooled the precusor component which it combines, before placing in the said plate and/or building a bridge is done at the desire level for complete building a bridge after this. The hydrogel which this partly building a bridge does is frozen and is frozen is dried. After the freeze drying, the said hydrogel is adjusted in order substantially to complete building a bridge, the structure of 1 or more, for example, is formed to the plug, the anastaltic or the other medical device etc. For example, the said hydrogel cuts off as the structure machining, rolling, tucking and compressing, and/or scooping out is done, is installed by the delivery device, is introduced by internal, the said structure transplantation or delivery is done to internal.< Selective figure > Figure 4医療用に患者の体内に導入し得る凍結乾燥したヒドロゲル及びこれによる構造体の製造方法を提供する。架橋を開始するために前駆体成分を組合せる。組合せた前駆体成分を冷却した皿に載せ、該皿に載せる前及び/又はこの後で完全な架橋に対する所望レベルで架橋が行われる。この部分的に架橋を行ったヒドロゲルが冷凍され凍結乾燥される。凍結乾燥後、該ヒドロゲルは実質的に架橋を完了するために調整され、1以上の構造体、例えば、プラグ、止血剤、又は他の医療装置などに形成される。例えば、該ヒドロゲルは構造体として切断、機械加工、圧延、折り込み、圧縮、及び/又はくり抜きが行われ、送達装置に装着され、体内に導入され、該構造体は体内に移植又は送達が行われる。【選択図】 図4
