ATOSSA THERAPEUTICS; INC.;ATOSSA THERAPEUTICS INC.;ATOSSA GENETICS, INC.
发明人:
QUAY, STEVEN C.
申请号:
CA3086655
公开号:
CA3086655A1
申请日:
2018.12.20
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to intraductal methods and compositions for treating subjects having breast disorders. Compositions comprise repolarizing agents and polarization blockading agents capable of repolarizing M2-macrophages to M1-macrophages in the tumor microenvironment, decreasing M2-macrophages, increasing M1-macrophages and/or increasing sensitivity to chemotherapy in the subject.