JANG, MYOUNG HO,张明浩,張明浩,SUNG, YOUNG CHUL,成永哲,成永哲,YANG, ZUNGYOON,梁祯允,梁禎允
申请号：
TW108101372
公开号：
TW201932129A
申请日:
2019.01.14
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention relates to a composition containing, as active ingredients, probiotics and a polypeptide with a binding ability to IgE. In particular, a synergistic effect of remarkably decreasing food allergy was identified at the time of combined administration of probiotics and a recombinant protein containing an extracellular domain of an alpha subunit of an IgE Fc receptor according to the present invention. Therefore, it is expected that the composition of the present invention is highly industrially applicable due to being able to exhibit a remarkable therapeutic effect on an IgE-mediated allergic disease as compared with conventional pharmaceutical compositions.本發明有關一種包含益生菌及具IgE結合能力之多肽作為活性成份的組成物。特別是，在合併投與益生菌與根據本發明之含有IgE Fc受體之α次單元的胞外區域之重組蛋白時，確定了明顯地減少食物過敏之協同作用。相較於習用藥學組成物，本發明之組成物由於在IgE介導的過敏性疾病上能夠表現出卓越的治療作用，因此預期其非常適合產業上之應用。
