The invention relates to a use of a Moutan Cortex extract for inhibiting adipocytes storing oil by applying an effective does of the Moutan Cortex extract to adipocytes. The Moutan Cortex extract is manufactured by at least one extraction step, one filtration step and one concentration step. Accordingly, the Moutan Cortex extract can be further utilized in cosmetic compositions, food additives or pharmaceutical compositionsfor inhibiting fat accumulation.本發明係有關於一種牡丹皮萃取物用以抑制脂肪細胞堆積油滴之用途,其係將一有效劑量之一牡丹皮萃取物作用至脂肪細胞中,其中,牡丹皮萃取物係藉由至少一萃取步驟、一過濾步驟以及一濃縮步驟而製得;藉此,可進一步利用牡丹皮萃取物作為抑制脂肪堆積之化妝材料組合物、食品添加物或醫藥組成物。
