ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR ANTIBODIES

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专利权人:

INC.;GENENTECH

发明人:

FUH, GERMAINE,LEE, CHINGWEI, V

申请号：

NZ58604708

公开号：

NZ586047A

申请日:

2008.12.01

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

An anti-vascular endothelial growth factor (VEGF) antibody. The antibody comprises the heavy chain hypervariable regions HVR-H1, HVR-H2 and HVR-H3 encoded by SEQ ID NOs: 1, 2 and 3 respectively and the light chain hypervariable regions, HVR-L2 and HVR-L3 encoded by SEQ ID NO: 6 and 7 respectively and the HVR-L1 encoded by SEQ ID NOs: 4 or 5. The antibody can be used for inhibiting angiogenesis or vascular permeability and for the treatment of a tumour, cancer or cell proliferative disorder.

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