Systems and methods for reduced pressure tissue treatments, including a multi- orientation canister. The canister includes an inlet for receiving fluids from a tissue site, and a main chamber in fluid communication with the inlet for receiving fluids from the inlet. The canister includes a filter chamber separated from the main chamber by one or more filter chamber walls. The one or more filter chamber walls includes a primary hole having a first diameter and a secondary hole having a second diameter smaller than the first diameter. The primary hole provides a first path of fluid communication between the filter chamber and the main chamber. The canister includes an outlet for providing fluid communication between the filter chamber and a reduced pressure source.
