STRONGLY INACTIVATED AND STILL HIGHLY IMMUNOGENIC VACCINE AND PROCESS OF MANUFACTURING THEREOF

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专利权人:

Géraldine GROUARD-VOGEL;Olivier DHELLIN;Pierre VANDEPAPELIÈRE;Bernard FANGET

发明人:

Géraldine GROUARD-VOGEL,Olivier DHELLIN,Bernard FANGET,Pierre VANDEPAPELIÈRE

申请号：

US12963192

公开号：

US20120148526A1

申请日:

2010.12.08

申请国别(地区):

US

年份:

2012

代理人:

摘要：

An immunogenic product includes TNFα coupled with KLH, wherein the TNFα is strongly inactivated, which means that the product shows less than 30% of cytolytic activity and/or an inactivation factor of more than 15000, in the conditions of TEST A. An emulsion and a vaccine including the immunogenic product and methods for preparing the immunogenic product are also described.

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