HUMAN BINDING MOLECULES CAPABLE OF NEUTRALIZING INFLUENZA VIRUS H5N1 AND USES THEREOF

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专利权人:

CRUCELL HOLLAND B.V.

发明人:

VAN DEN BRINK, EDWARD, NORBERT,DE KRUIF, CORNELIS ADRIAAN,THROSBY, MARK

申请号：

NZ57458107

公开号：

NZ574581A

申请日:

2007.09.06

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

An isolated human binding molecule capable of recognizing and binding to an epitope in the HA2 subunit of the influenza haemagglutinin protein (HA), characterized in that said binding molecule has neutralizing activity against an influenza virus comprising HA of the H5 subtype, such as H5N1, H5N2, H5N8, and H5N9, and in that said binding molecule comprises the VH germline VH1-69.

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