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The use of kauranes compounds in the manufacture of medicament for treatment of cardiac hypertropy and pulmonary hypertension
专利权人:
Key-Pharma Biomedical Inc.;Wen Tan
发明人:
Tan, Wen
申请号:
AU2016318815
公开号:
AU2016318815A1
申请日:
2016.09.07
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The invention relates novel pharmaceutical use of kaurane compounds of formula (I) in treating and preventing cardiac hypertrophy and myocardium remodeling. The said compounds also can significantly ameliorate pulmonary hypertension and preventing vascular hypertrophy. The said compounds can also be used to suppress fibrosis and to treat erection dysfunction, neurological degenerations and other related diseases by modulating cGMP or cAMP signal pathway and/or by reducing reactive oxygen species (ROS). Wherein R
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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