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PROCESS FOR PREPARING INJECTABLE FOSAPREPITANT DIMEGLUMINE COMPOSITIONS HAVING IMPROVED STORAGE STABILITY
专利权人:
Navinta III Inc
发明人:
Sandipkumar Arvindbhai Patel
申请号:
US16774760
公开号:
US20200237788A1
申请日:
2020.01.28
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Solid compositions having about 150 mg to about 245 mg Fosaprepitant that are stable after storage at about 25° C. for 6 months and processes for preparing solid Fosaprepitant compositions that are stable after long term storage at room temperature. The processes include freezing a Fosaprepitant solution in the primary packaging container at a first freezing temperature; applying vacuum at second temperature that is higher than the freezing temperature; fully stoppering the primary packaging container; and sealing the stoppered primary packaging container.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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